The Actives We Build On
Branded. Patented. Published.
We don't formulate with generic raw materials. Ever. Every product starts with a branded, patented, clinically studied active — named on the label, dosed to its published human trial, and traceable to its licensor. Below are the houses we source from and the specific actives we stand behind.
Identity
What is it, exactly?
The compound is confirmed against a certified reference — by spectrum and chromatographic fingerprint — before anything else happens.
Potency
How much is really there?
The active is quantified by HPLC and standardised to a declared strength, so the dose on the label is the dose in the capsule.
Proof
Can you show it?
Identity, potency and purity arrive in writing — a Certificate of Analysis tied to a traceable batch. Every time.
Bangalore, India · New Jersey, USA
Sami-Sabinsa Group
Founded 1988 by Dr. Muhammed Majeed. 400+ granted patents, 900+ trademarks. The most-studied actives of their kind — and we can show you the papers.
Curcumin C3 Complex®
Curcuma longa extract, standardized to 95% total curcuminoids (curcumin, demethoxy- and bisdemethoxycurcumin)
Improved WOMAC & VAS knee-pain scores vs placebo
Double-blind RCT (C3 + BioPerine) · n=53 · 8 wks · Panda 2014
Antioxidant and joint-comfort support. The most clinically documented curcumin brand — dozens of human trials, including NIH-funded studies. Self-affirmed GRAS.
BioPerine®
Piper nigrum fruit extract, standardized to 95% piperine
2000% higher curcumin bioavailability
Human pharmacokinetic crossover · Shoba & Majeed, Planta Medica 1998
Raises the bioavailability of co-administered nutrients. Patented 1996; ~60 human studies. Self-affirmed GRAS.
LactoSpore®
Bacillus coagulans MTCC 5856, ~15 billion CFU/g
45% fewer bowel movements vs baseline (p=0.003)
Double-blind RCT · IBS · n=36 · 90 days · Majeed 2016
Supports digestive balance. Spore-form: heat- and acid-resistant, shelf-stable, no refrigeration. GRAS; Non-GMO Project Verified.
DigeZyme®
Multi-enzyme complex: amylase, protease, lipase, cellulase, lactase
Lower dyspepsia symptom severity vs placebo
Double-blind RCT · functional dyspepsia · n=40 · 60 days · Majeed 2018
Aids digestion of starch, protein, fat, fibre and lactose. Randomised, double-blind, placebo-controlled trial in functional dyspepsia. All-vegetarian source.
Boswellin®
Boswellia serrata gum-resin extract, standardized to boswellic acids (AKBA grades available)
73.6% WOMAC improvement vs 22% on placebo
Double-blind RCT · knee OA · 90 days · Majeed 2024
Supports joint comfort and mobility. Clinically studied in osteoarthritis; researched grades include Boswellin Super and PS.
ForsLean®
Coleus forskohlii root extract, standardized to 10% forskolin
Lower body-fat % and fat mass (DXA)
Double-blind RCT · n=30 men · 12 wks · Godard 2005
Supports lean body mass and healthy body composition. Patented use (US 5,804,596) plus later energy-balance patents; multiple clinical studies.
Hyderabad, India
Ixoreal Biomed
Makers of the world's most clinically studied ashwagandha — 50+ gold-standard human trials behind a single root-only extract. Water-based green chemistry; no alcohol, no synthetic solvents.
KSM-66® Ashwagandha
Full-spectrum, root-only Withania somnifera, standardized to >5% withanolides by HPLC; water-based extraction
27.9% lower serum cortisol vs placebo
Double-blind RCT · n=64 · 60 days · Chandrasekhar 2012
Supports stress resilience and lowers serum cortisol. 50+ human clinical trials, 46+ certifications, self-affirmed GRAS; used in 4,500+ products worldwide.
SRI-81™ Shatavari
Organic-certified, root-only Asparagus racemosus extract, green-chemistry processed; clinical dose 300 mg/day
52.6% vs 25% breastfeeding satisfaction (p=0.008)
Double-blind RCT · n=120 postpartum · Ajgaonkar 2025
Supports women's health and postpartum lactation. Organic-certified, root-only; ~10–18 clinical studies and 8 years of R&D.
Milan, Italy
Indena S.p.A.
Phytosome® delivery science since 1921. Standardized botanical actives studied in published human trials — absorption you can measure, not assume.
Meriva®
Curcumin Phytosome® — curcumin complexed with sunflower phospholipids
29× higher curcuminoid absorption vs standard
Human PK crossover study · Cuomo 2011 · J Nat Prod
Up to 29× higher curcumin absorption versus unformulated; studied for joint comfort across multiple human trials.
Mirtoselect®
Standardized bilberry (Vaccinium myrtillus) extract, 36% anthocyanins
+71% tear secretion vs placebo (Schirmer's)
Double-blind RCT · n=22 · 4 wks · Riva 2017
Antioxidant support for eye comfort and microcirculation — the bilberry standard used in published clinical research.
Casperome®
Boswellia serrata Phytosome® (boswellic acids + phospholipids)
IBS symptoms in 12.5% vs 58% on placebo
Double-blind RCT · mild IBS · Belcaro & Riva 2019
Enhanced-absorption boswellia studied for joint comfort and digestive ease.
Quercefit®
Quercetin Phytosome®
Up to 20× higher quercetin absorption
Human bioavailability study · Riva 2019
Up to ~20× higher quercetin absorption; studied for antioxidant and immune support.
Relissa®
Melissa officinalis (lemon balm) Phytosome®
Sleep-quality score (PSQI) fell 10.9 → 3.5
Double-blind RCT · n=100 · 3 wks · Front. Pharmacol. 2023
Lemon-balm phytosome studied for sleep quality and everyday stress.
New Hampton, New York, USA
Balchem Corporation
Mineral-chelation and choline science since 1956. 150+ patents, 160+ studies across the Albion portfolio — absorption you can prove.
Albion® TRAACS®
Fully reacted amino-acid chelated minerals (mineral bisglycinates) — The Real Amino Acid Chelate System
Up to 8.8× more absorbable magnesium vs oxide
Albion absorption studies · chelate vs inorganic salts
Higher mineral absorption and gentler GI tolerance than inorganic salts. 150+ patents, 160+ studies; the TRAACS seal verifies a fully-reacted chelate.
Ferrochel®
Ferrous bisglycinate chelate (iron bound to two glycine molecules)
4.7× higher iron absorption vs ferrous sulfate
Stable-isotope human study · Bovell-Benjamin, AJCN 2000
Highly absorbable iron with less GI upset and no metallic taste. Self-affirmed GRAS; WHO-recognised for absorption; EFSA positive opinion.
K2VITAL®
Vitamin K2 as menaquinone-7 (MK-7), 99.7% all-trans
4.1% lower arterial stiffness over 3 years
Double-blind RCT · n=244 · 180 µg/day · Knapen 2015
Directs calcium toward bone and away from arteries. Patented purity and stability (K2VITAL DELTA microencapsulation); peer-reviewed MK-7 research.
VitaCholine®
USP-grade choline (bitartrate and chloride salts), an essential methyl donor
Better child attention at age 7 (p=0.02)
RCT maternal feeding trial · 3rd-trimester choline · Caudill 2022
Supports brain, liver and prenatal neurodevelopment. FDA-recognised essential nutrient; the choline behind major prenatal brands; patented low-odour technology.
India
Gramen Botanicals
Wild-harvested Berberis aristata, water-only extraction — the source rigour behind HIMABERB®, the world's only C-14-tested berberine.
HIMABERB® Berberine
Berberine HCl 97% from wild Berberis aristata; water-only extraction; C-14 tested for natural origin
33% better HOMA-IR insulin sensitivity
12-week human RCT (HIMABERB®)
Supports healthy glucose and lipid metabolism. Wild-sourced, water-only extraction; the world's only C-14-verified berberine.
Global (Danisco)
IFF — HOWARU®
HOWARU® probiotic strains, characterized to the strain and studied in human trials — manufactured to pharmaceutical standards.
L. acidophilus NCFM®
Lactobacillus acidophilus NCFM® — a fully sequenced, named strain
Reduced bloating severity vs placebo
Double-blind RCT (NCFM + Bi-07) · n=60 · Ringel-Kulka 2011
One of the most-studied probiotic strains in the world; supports digestive and immune health.
HOWARU® Bifido
Bifidobacterium animalis subsp. lactis HN019
28 h faster whole-gut transit vs placebo
Triple-blind RCT · n=100 · 14 days · Waller 2011
Studied for digestive transit and immune support in human trials.
L. rhamnosus HN001
Lactobacillus rhamnosus HN001 — a clinically documented strain
~50% lower infant eczema to age 2
Double-blind RCT · n=474 infants · Wickens 2008
Studied for immune and maternal-infant health.
HOWARU® Restore
Defined multi-strain probiotic blend
Fewer diarrhoea days vs placebo (3.5 vs 12)
Double-blind RCT · 4-strain blend · Barker 2017
Formulated and studied to support gut balance during disruption.
Hørsholm, Denmark
Chr. Hansen (Novonesis)
Some of the most-documented probiotic strains in the world — strain-level traceability backed by decades of clinical literature.
LGG®
Lactobacillus rhamnosus GG
51% lower antibiotic-associated diarrhoea risk
Meta-analysis · 12 RCTs · n=1,499 · Szajewska 2015
The most clinically studied probiotic strain globally; supports digestive and immune health.
BB-12®
Bifidobacterium animalis subsp. lactis BB-12®
55% higher odds of improved bowel regularity
Double-blind RCT · n=1,248 · 4 wks · Eskesen 2015
The world's most documented bifidobacterium; supports digestive wellbeing.
LA-5®
Lactobacillus acidophilus LA-5®
7.5% lower LDL cholesterol vs control
Double-blind RCT · n=60 · LA-5 + BB-12 yogurt · Ejtahed 2011
Widely studied acidophilus strain for digestive balance.
L. casei 431®
Lactobacillus paracasei subsp. paracasei 431®
Cold symptoms 6.4 vs 7.3 days vs placebo
Double-blind RCT · n=1,104 · 42 days · Jespersen 2015
Casei strain studied for immune support.
Hyderabad, India
Unique Biotech
Indian-made, clinically studied probiotic and spore strains — DSIR-recognised R&D with strain-level documentation.
Bacillus coagulans Unique IS-2®
Spore-forming Bacillus coagulans strain Unique IS-2®
84.9% vs 12.7% had ≥50% less abdominal pain
Double-blind RCT · n=108 · 8 wks · Madempudi 2019, Sci. Reports
Shelf-stable spore probiotic studied in IBS and digestive health.
Bacillus clausii UBBC-07
Spore-forming Bacillus clausii strain UBBC-07
~24% lower stool frequency by day 4
Double-blind RCT · paediatric diarrhoea · 5 days · 2019
Studied to support gut balance during and after antibiotic use.
Saccharomyces boulardii
Probiotic yeast Saccharomyces boulardii (Unique Biotech strain)
Probiotic yeast studied for digestive resilience and diarrhoea-associated balance.
Clinical outcomes shown refer to published human studies on the specific branded active named, at the dose studied — not to any finished product, and not as a claim to diagnose, treat, cure, or prevent any disease. All trademarks are the property of their respective owners; branded actives are shown under authorized-use agreements with each licensor.
Name the active. We'll show you the paper.
Tell us the category and target markets. We'll propose a formulation built on the branded actives that fit — at the dose their human trials used.